Research

We develop neuroimaging biomarkers and validate ultrasound-based therapies for neurological disease.

01 — Advanced Neuroimaging

Reading the brain with multimodal PET/MRI

Multimodal PET/MRI biomarkers for Parkinson's disease and its progression.

We integrate computational modeling and AI for personalized medicine.

FDOPA / FDG PETDiffusion MRIfMRIAI biomarkers
Selected figures · each links to its paper
Selected figures · each links to its paper
02 — HIFU Thermoablation

Incision-free neurosurgery, redefined

HIFU enables precise, incision-free lesioning of deep brain structures.

We build predictive lesion models and decision-support systems, with 400+ cases of experience.

MR ThermometryLesion Prediction400+ cases
03 — Blood–Brain Barrier Opening

Delivering therapy where it couldn't reach

Low-intensity ultrasound + microbubbles transiently open the BBB for targeted delivery.

We focus on quantitative permeability metrics and AI-driven decision tools.

MicrobubblesGene TherapyAcoustic Monitoring
Selected figures · each links to its paper
Selected figure · links to its source
04 — Ultrasound Neuromodulation

Mapping circuits, finding targets

TUS reversibly modulates cortical excitability with high spatial precision.

We use TUS to identify and validate therapeutic targets before definitive interventions.

tFUSTarget ValidationBrain Mapping

See our research in action

Explore the projects translating these lines into reality.

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